This is also another form of IVF treatment whereby a single sperm is injected microscopically into a mature egg by forced entry performed by a qualified embryologist, using a special instrument called micromanipulators.
ICSI procedure is performed for the following conditions:
- Low sperm count
- Unexplained fertilization failure by conventional IVF or poor fertilization in previous IVF cycles
- Severe structural abnormalities of the sperm
- Low sperm motility or total sperm immotility such as Kartagener’s Syndrome, an inherited condition where defective sperm tail that hampers tail movement.
- Epididymal or testicular sperm obtained from azoospermic males (no sperm present in the semen).
- Retrograde ejaculation (where there is a reverse direction of ejaculate into the bladder)
After ICSI, the eggs are then checked to see if fertilization had occurred. Fertilized eggs are then separated from unfertilized eggs for further culturing.
On the day of embryo transfer (which can take place 2 to 5 days later), between 2 to 3 embryos are chosen to be replaced into the uterus.