Skip to content

MESA, PESA, TESA & TESE Reproductive Surgeries for Men

Male Reproductive Surgery includes minimally invasive procedures such as MESA, PESA, TESA, and TESE to retrieve sperm and treat male infertility.

Helpful tools

What is Reproductive Surgery?

Reproductive surgery for males refers to surgical procedures or microsurgical sperm retrieval techniques designed to retrieve sperm or correct anatomical issues that affect fertility.

At Sunfert, we offer advanced microsurgical and minimally invasive techniques to help men with obstructive or non-obstructive fertility challenges achieve biological parenthood.

These procedures are performed by our experienced fertility specialists using precision technology to maximise the chances of successful sperm retrieval.

 

Male reproductive surgery is typically recommended when:

  • sperm is absent in the ejaculate (Azoospermia)
  • there is a blockage preventing sperm release
  • previous sperm analysis shows severely low sperm count
  • assisted reproductive treatment requires direct sperm retrieval

 

Notes:

  • Azoospermia: A condition where no sperm is found in the semen, leading to male infertility.
  • Non-obstructive Azoospermia: A form of azoospermia caused by impaired or absent sperm production in the testes.
  • Obstructive Azoospermia: A form of azoospermia caused by a blockage that prevents sperm from being present in the semen despite normal sperm production.

Types of Reproductive Surgery for Males

There are 4 main types of minimally invasive reproductive surgery for males available at Sunfert:

  1. Microsurgical Testicular Sperm Extraction (MESA)

  2. Percutaneous Testicular Sperm Aspiration (PESA)

  3. Testicular Sperm Aspiration (TESA)

  4. Testicular Sperm Extraction (TESE)

What is MESA, PESA, TESA and TESE?

Microsurgical Testicular Sperm Extraction (MESA)

MESA is an advanced surgical procedure where we use an operating microscope to carefully identify and extract sperm directly from the testicular tissue.

This technique allows us to precisely locate tiny areas where sperm production may still be occurring, even in challenging cases.

 

Percutaneous Testicular Sperm Aspiration (PESA)

PESA is a minimally invasive procedure where we use a fine needle to extract sperm from the epididymis. It is performed under local anaesthesia and does not require open surgery.

Note:

  • Local anesthesia is used to temporarily numb a specific area of the skin, underlying tissue, and peripheral nerves to reduce pain during minor procedures.

 

Testicular Sperm Aspiration (TESA)

TESA involves using a needle to extract sperm directly from the testicle. Unlike open surgical methods, TESA is performed through needle aspiration, making it a straightforward and minimally invasive option.

 

Testicular Sperm Extraction (TESE)

TESE is a minor surgical procedure where we remove a small biopsy of testicular tissue to extract sperm. The tissue sample is carefully examined in our laboratory to identify viable sperm for fertilisation.

Sunfert types of male reproductive surgery including MESA, PESA, TESA, and TESE for sperm retrieval and fertility treatment

The Difference Between MESA, PESA, TESA and TESE

AspectMESAPESATESATESE
Procedure MethodMicrosurgical retrieval of sperm from the epididymisNeedle aspiration of sperm from the epididymisNeedle aspiration of sperm directly from testicular tissueSurgical biopsy of testicular tissue to extract sperm
When It’s UsedObstructive azoospermia (blocked sperm ducts)Obstructive azoospermiaEpididymal sperm unavailable or prior procedure failedNon-obstructive azoospermia (low or no sperm production)
Key FeaturesHigh-quality sperm, requires microsurgeryLess invasive, quick outpatient procedureSimple outpatient procedure, sperm from testicleMultiple biopsies may be performed for better yield
Recovery TimeMinor recovery, small incisionMinimal discomfort, fast recoveryMinor soreness, local anesthesiaSmall surgical site, short recovery

Take the Next Step with Our Fertility Specialists

If you are facing fertility challenges, start with a consultation at Sunfert. We will guide you through your fertility journey with expertise and compassionate care. 

Make an appointment with our Fertility Specialist today and take the next step toward your parenthood goals.

What is the difference between MESA, PESA, TESA, and TESE?

Microsurgical Testicular Sperm Extraction (MESA): Uses microsurgery to retrieve sperm from the epididymis.
Percutaneous Testicular Sperm Aspiration (PESA): Uses a fine needle to aspirate sperm from the epididymis.
Testicular Sperm Aspiration (TESA): Retrieves sperm directly from the testicle using needle aspiration.
Testicular Sperm Extraction (TESE): Involves taking a small biopsy of testicular tissue to locate sperm.
Each technique is selected based on the underlying cause of infertility.

Is MESA painful and how long is recovery?

Microsurgical Testicular Sperm Extraction (MESA) is performed under anaesthesia to ensure minimal discomfort during the procedure.
Most patients experience mild soreness afterwards, and recovery is usually quick, with many returning to light activities within a few days.

Is PESA safe for treating obstructive azoospermia?

Yes, Percutaneous Testicular Sperm Aspiration (PESA) is a safe and commonly used procedure for obstructive azoospermia.

It is minimally invasive, performed under local anaesthesia, and does not require open surgery.

Recovery is typically fast with minimal discomfort.

Can TESA be repeated if no sperm is found?

Yes, Testicular Sperm Aspiration (TESA) can be repeated if clinically appropriate.

The decision depends on medical evaluation, underlying fertility condition, and previous sperm retrieval outcomes.

Our fertility specialist will advise on timing and suitability for repeat procedures.

When is TESE recommended instead of needle-based sperm retrieval?

Testicular Sperm Extraction (TESE) is usually recommended when needle-based methods like TESA or PESA do not successfully retrieve sperm, or when a larger tissue sample is needed to improve the chances of finding viable sperm, especially in cases of non-obstructive azoospermia.

Ready to start your fertility journey?

Book now

The Biological Clock

This tool indicates:

  • Natural conception per month if you have no fertility issues
  • IVF success rate at the same age
  • When to seek help after months of unsuccessful attempts

If you are concerned at any stage – we recommend booking a doctor appointment or a free nurse consultation. The sooner you make a plan the better your chances in the long term.

When to seek advice early

If you have polycystic ovaries, endometriosis, or have been through a cancer diagnosis; we recommend you get in touch quickly so we can talk you through all your options and give you the greatest possible chance of success.

If you’re a single woman considering motherhood in the future; it’s best to approach us early and consider egg freezing as this can be an option for you while you have a higher ovarian reserve and healthier eggs.

Set your age and the months you’ve been trying to conceive
26
2
Your chance of having a baby per month for fertile couples
Your chance of having a baby per IVF cycle (if experiencing infertility)

Body Mass Index calculator

Being overweight or underweight can reduce fertility, so it is important to keep your body weight within the normal healthy range.

Body Mass Index (BMI) is an indication of your body weight and can be calculated by dividing weight by height. You should aim for a BMI of between 20 and 25, as this will optimise your chances of conception.

Woman’s BMI below 19

Even in these modern times, nature knows best. If a woman's BMI falls below 19, the body senses famine and ovulation is switched off to prevent the risk of having a baby with malnutrition. Excessive exercise can reduce body fat and increase muscle mass to a point where periods cease for the same reason. Risk of miscarriage is also increased in women with a low BMI.

Being underweight

If a woman's BMI falls below 19, the body senses famine and ovulation is switched off to prevent the risk of having a baby with malnutrition. Excessive exercise can reduce body fat and increase muscle mass to a point where periods cease for the same reason. Risk of miscarriage is also increased in women with a low BMI.

BMI’s greater than 30

This can reduce fertility by 50%. Pregnancy for women with a 30+ BMI is often associated with problems such as maternal diabetes, high blood pressure, big babies and increased risk of caesarean section.

Add your height and weight to calculate your BMI