What Are Recurrent Miscarriages?
- Definition: Recurrent Miscarriages (RM) or Recurrent Pregnancy Losses (RPL) are defined as having two or more consecutive pregnancy losses before 20 weeks of gestation by Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG)
- Prevalence: According to RANZCOG, approximately 1% - 4% of couples experience recurrent miscarriages, affecting both physical and emotional well-being.
- Emotional Impact: We understand that repeated pregnancy loss can lead to stress, anxiety, and uncertainty, making early guidance and support essential.
Why Do Recurrent Miscarriages Happen?
- Genetic Factors: Chromosomal abnormalities in embryos can be a significant contributor.
- Uterine Issues: Structural problems like fibroids, septum, or scar tissue may interfere with implantation.
- Hormonal Imbalances: Thyroid disorders or luteal phase defects can increase miscarriage risk.
- Immune and Blood Disorders: Conditions such as antiphospholipid syndrome can affect pregnancy maintenance.
- Lifestyle Factors: Smoking, excessive alcohol, obesity, and uncontrolled stress can also play a role.
Who Has A Higher Risk of Recurrent Miscarriages?
- Women Over 35: Maternal age increases the likelihood of chromosomal abnormalities.
- Couples With Previous Miscarriages: Risk of recurrence is higher after two or more pregnancy losses.
- Individuals With Underlying Health Conditions: Thyroid disorders, diabetes, or clotting disorders require careful monitoring.
When Should You Seek Help?
- After Two Miscarriages: It is recommended to consult a fertility specialist after two consecutive losses.
- During Preconception Planning: Early fertility assessment can help identify risks and improve pregnancy outcomes.
How Can Couples Reduce the Risk of Recurrent Miscarriages?
- Comprehensive Fertility Assessment: Blood tests, hormonal tests, and uterine imaging.
- Genetic Counselling: Identify potential chromosomal issues in both partners.
- Lifestyle Optimisation: Balanced diet, regular exercise, and stress management.
- Advanced Testing Techniques: Combine IVF treatment with PGT-A
How PGT-A Can Help Patients To Reduce Miscarriage Risk?
Pre-implantation Genetic Testing for Aneuploidy (PGT-A):
- Helps identify embryos with chromosomal abnormalities before transfer.
- Increases the likelihood of a healthy pregnancy, reducing the emotional burden of repeated miscarriages.
Who Should Consider PGT-A?
PGT-A is usually for:
- Women over 35 years old
- Couples with multiple IVF failures
- Couples with recurrent miscarriages
- Couples who want to reduce the risk of having a baby with chromosome abnormality such as Down’s Syndrome
Want to know about PGT-A? Click here to learn more.
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Book a consultationDato' Dr Wong Pak Seng
Founder of Sunfert Group & Fertility Specialist- Sunfert@Bangsar South
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Book a consultationDr Eeson Sinthamoney
Group Medical Director & Fertility Specialist- Sunfert@Bangsar South
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Book a consultationDr Lim Lei Jun
Medical Director (Sunfert Bangsar South) & Fertility Specialist- Sunfert@Bangsar South
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Book a consultationDr Sumithra Devi Valiapan
Consultant Obstetrics, Gynaecology & Fertility Specialist- Sunfert@Bangsar South
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Book a consultationDr Haris Njoo Suharjono
Medical Director (Sunfert Kuching) & Fertility Specialist- Sunfert@Kuching
Is recurrent miscarriage only a female issue?
No. Male genetic factors and sperm quality can also contribute, making assessment of both partners essential.
Who should consider PGT-A during IVF?
PGT-A is commonly recommended for individuals or couples who:
- are of advanced maternal age
- have experienced recurrent miscarriages
- have had repeated implantation failure
- previously had pregnancies affected by chromosomal abnormalities
- want to prioritise the most viable embryos
At Sunfert, we aim to ensure that any additional procedures are only advised when there is clear clinical benefit, so patients are not undergoing or paying for steps that are not necessary for their fertility journey and treatment.
Can PGT-A guarantee a successful pregnancy?
No, PGT-A does not guarantee pregnancy. While it improves the selection of chromosomally normal embryos and increases the implantation rate, other factors such as uterine health, embryo quality, and overall medical conditions also influence the overall IVF success rates.
How long does it take to get PGT-A results?
PGT-A results are typically available within 2 to 3 weeks after the embryo biopsy.
This timeframe allows for detailed genetic analysis and accurate reporting to guide the next step in the IVF treatment plan.